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Fakultät BCI
Technical Biocatalysis Group

Dr.-Ing. Lea Winand

Awards

- 2023: Dissertation Prize of the Faculty of Biological and Chemical Engineering at TU Dortmund University

- 2023: Ulfert Onken Prize for Biotechnology

Publications

L. Winand, S. Theisen, S. Lütz, K. Rosenthal, M. Nett
Immobilization of the Amidohydrolase MxcM and Its Application for Biocatalytic Flow Synthesis of Pseudochelin A
Catalysts. 2023, 13(2), 229. doi:10.3390/catal13020229

L. Winand, L. Lernoud, S. A. Meyners, K. Kuhr, W. Hiller, M. Nett
Myxococcus xanthus as Host for the Production of Benzoxazoles
ChemBioChem. 2023, 24(5), e202200635. doi:10.1002/cbic.202200635

D. J. Vollmann, L. Winand, M. Nett
Emerging concepts in the semisynthetic and mutasynthetic production of natural products
Curr. Opin. Biotech. 2022, 77, 102761. doi:10.1016/j.copbio.2022.102761

B. K. Lombe, L. Winand, J. Diettrich, M. Töbermann, W. Hiller, M. Kaiser, M. Nett
Discovery, Biosynthetic Origin, and Heterologous Production of Massinidine, an Antiplasmodial Alkaloid
Org. Lett. 2022, 24(15), 2935-2939. doi:10.1021/acs.orglett.2c00963

L. Winand, P. Schneider, S. Kruth, N.-J. Greven, W. Hiller, M. Kaiser, J. Pietruszka, M. Nett
Mutasynthesis of Physostigmines in Myxococcus xanthus
Org. Lett. 2021, 23(16), 6563-6567. doi:10.1021/acs.orglett.1c02374

L. Winand, D. J. Vollmann, J. Hentschel, M. Nett
Characterization of a Solvent-Tolerant Amidohydrolase Involved in Natural Product Heterocycle Formation
Catalysts. 2021, 11(8), 892. doi:10.3390/catal11080892

L. Winand, A. Sester, M. Nett
Bioengineering of Anti-Inflammatory Natural Products
ChemMedChem. 2021, 16(5), 767-776. doi:10.1002/cmdc.202000771

A. Sester, L. Winand, S. Pace, W. Hiller, O. Werz, M. Nett
Myxochelin- and Pseudochelin-Derived Lipoxygenase Inhibitors from a Genetically Engineered Myxococcus xanthus Strain
J. Nat. Prod. 2019, 82(9), 2544-2549. doi:10.1021/acs.jnatprod.9b00403

J. Korp, L. Winand, A. Sester, M. Nett
Engineering Pseudochelin Production in Myxococcus xanthus
Appl. Environ. Microbiol. 2018, 84(22). doi:10.1128/AEM.01789-18