Beiträge in wissenschaftlichen Fachzeitschriften, Buchkapitel und Patente

2024

(87)   Steinmetz T, Lindig A, Lütz S, Nett M. Molecular Networking-Guided Discovery of Kyonggic Acids in Massilia spp. European J Org Chem. 2024 March 21; doi:10.1002/ejoc.202400017

2023

(86)   Steinmetz T, Lombe BK, Nett M. Intermediates and shunt products of massiliachelin biosynthesis in Massilia sp. NR 4-1. Beilstein J Org Chem. 2023 Jun 23;19:909-917. doi: 10.3762/bjoc.19.69. PMID: 37377775; PMCID: PMC10291242.

(85)   Kruth S, Nett M. Aurachins, Bacterial Antibiotics Interfering with Electron Transport Processes. Antibiotics (Basel). 2023 Jun 17;12(6):1067. doi: 10.3390/antibiotics12061067. PMID: 37370386; PMCID: PMC10295502.

(84)   Winand L, Theisen S, Lütz S, Rosenthal K, Nett M. (2023), "Immobilization of the Amidohydrolase MxcM and Its Application for Biocatalytic Flow Synthesis of Pseudochelin A" Catalysts 13, no. 2: 229. doi: 10.3390/catal13020229

(83)   Kruth S, Zimmermann CJ, Kuhr K, Hiller W, Lütz S, Pietruszka J, Kaiser M, Nett M. Generation of Aurachin Derivatives by Whole-Cell Biotransformation and Evaluation of Their Antiprotozoal Properties. Molecules. 2023 Jan 20;28(3):1066. doi: 10.3390/molecules28031066. PMID: 36770729; PMCID: PMC9919615.

2022

(82)   Winand L, Lernoud L, Meyners SA, Kuhr K, Hiller W, Nett M. Myxococcus xanthus as Host for the Production of Benzoxazoles. Chembiochem. 2023 Mar 1;24(5):e202200635. doi: 10.1002/cbic.202200635. Epub 2022 Dec 29. PMID: 36484355.

(81)   Kruth S, Schibajew L, Nett M. Biocatalytic production of the antibiotic aurachin D in Escherichia coli. AMB Express. 2022 Nov 3;12(1):138. doi: 10.1186/s13568-022-01478-8. PMID: 36327024; PMCID: PMC9633902.

(80)   Vollmann DJ, Winand L, Nett M. Emerging concepts in the semisynthetic and mutasynthetic production of natural products. Curr Opin Biotechnol. 2022 Oct;77:102761. doi: 10.1016/j.copbio.2022.102761. Epub 2022 Jul 30. PMID: 35917622.

(79)   Kinner A, Nerke P, Siedentop R, Steinmetz T, Classen T, Rosenthal K, Nett M, Pietruszka J, Lütz S. Recent Advances in Biocatalysis for Drug Synthesis. Biomedicines. 2022 Apr 21;10(5):964. doi: 10.3390/biomedicines10050964. PMID: 35625702; PMCID: PMC9138302.

(78)   Lombe BK, Winand L, Diettrich J, Töbermann M, Hiller W, Kaiser M, Nett M. Discovery, Biosynthetic Origin, and Heterologous Production of Massinidine, an Antiplasmodial Alkaloid. Org Lett. 2022 Apr 22;24(15):2935-2939. doi: 10.1021/acs.orglett.2c00963. Epub 2022 Apr 12. PMID: 35412834.

(77)   Steinmetz T, Hiller W, Nett M. Amamistatins isolated from Nocardia altamirensis. Beilstein J Org Chem. 2022 Mar 30;18:360-367. doi: 10.3762/bjoc.18.40. PMID: 35422885; PMCID: PMC8978914.

2021

(76)   Vollmann DJ, Busche T, Rückert C, Nett M. Complete Genome Sequence of the Nonmotile Myxococcus xanthus Strain NM. Microbiol Resour Announc. 2021 Oct 28;10(43):e0098921. doi: 10.1128/MRA.00989-21. Epub 2021 Oct 28. PMID: 34709053; PMCID: PMC8552703.

(75)   Winand L, Schneider P, Kruth S, Greven NJ, Hiller W, Kaiser M, Pietruszka J, Nett M. Mutasynthesis of Physostigmines in Myxococcus xanthus. Org Lett. 2021 Aug 20;23(16):6563-6567. doi: 10.1021/acs.orglett.1c02374. Epub 2021 Aug 6. PMID: 34355569.

(74)   Tippelt A, Nett M. Saccharomyces cerevisiae as host for the recombinant production of polyketides and nonribosomal peptides. Microb Cell Fact. 2021 Aug 19;20(1):161. doi: 10.1186/s12934-021-01650-y. PMID: 34412657; PMCID: PMC8374128.

(73)   Winand L, Vollmann DJ, Hentschel J, Nett M (2021) Characterization of a solvent-tolerant amidohydrolase involved in natural product heterocycle formation. Catalysts 11, 892. doi: 10.3390/catal11080892

(72)   Winand L, Sester A, Nett M. Bioengineering of Anti-Inflammatory Natural Products. ChemMedChem. 2021 Mar 3;16(5):767-776. doi: 10.1002/cmdc.202000771. Epub 2020 Dec 16. PMID: 33210441; PMCID: PMC7986114.

2020

(71)   Rosenthal K, Becker M, Rolf J, Siedentop R, Hillen M, Nett M, Lütz S. Catalytic Promiscuity of cGAS: A Facile Enzymatic Synthesis of 2'-3'-Linked Cyclic Dinucleotides. Chembiochem. 2020 Nov 16;21(22):3225-3228. doi: 10.1002/cbic.202000433. Epub 2020 Aug 4. PMID: 32633874; PMCID: PMC7754487.

(70)   Sester A, Stüer-Patowsky K, Hiller W, Kloss F, Lütz S, Nett M. Biosynthetic Plasticity Enables Production of Fluorinated Aurachins. Chembiochem. 2020 Aug 17;21(16):2268-2273. doi: 10.1002/cbic.202000166. Epub 2020 May 5. PMID: 32216075; PMCID: PMC7496329.

(69)   Tippelt A, Nett M, Vela Gurovic MS. Complete Genome Sequence of the Lignocellulose-Degrading Actinomycete Streptomyces albus CAS922. Microbiol Resour Announc. 2020 May 21;9(21):e00227-20. doi: 10.1128/MRA.00227-20. PMID: 32439662; PMCID: PMC7242664.

(68)   Tippelt A, Busche T, Rückert C, Nett M. Complete Genome Sequence of the Cryptophycin-Producing Cyanobacterium Nostoc sp. Strain ATCC 53789. Microbiol Resour Announc. 2020 Apr 2;9(14):e00040-20. doi: 10.1128/MRA.00040-20. PMID: 32241855; PMCID: PMC7118181.

(67)   Sester A, Korp J, Nett M (2020) Secondary metabolism of predatory bacteria. In: The Ecology of Predation at the Microscale, edited by Jurkevitch E, Mitchell RJ, Springer Nature Switzerland, ISBN 978-3-030-45598-9

2019

(66)   Kallscheuer N, Kage H, Milke L, Nett M, Marienhagen J. Microbial synthesis of the type I polyketide 6-methylsalicylate with Corynebacterium glutamicum. Appl Microbiol Biotechnol. 2019 Dec;103(23-24):9619-9631. doi: 10.1007/s00253-019-10121-9. Epub 2019 Nov 4. PMID: 31686146.

(65)   Sester A, Winand L, Pace S, Hiller W, Werz O, Nett M. Myxochelin- and Pseudochelin-Derived Lipoxygenase Inhibitors from a Genetically Engineered Myxococcus xanthus Strain. J Nat Prod. 2019 Sep 27;82(9):2544-2549. doi: 10.1021/acs.jnatprod.9b00403. Epub 2019 Aug 29. PMID: 31465225.

(64)   Diettrich J, Kage H, Nett M. Genomics-inspired discovery of massiliachelin, an agrochelin epimer from Massilia sp. NR 4-1. Beilstein J Org Chem. 2019 Jun 13;15:1298-1303. doi: 10.3762/bjoc.15.128. PMID: 31293678; PMCID: PMC6604713.

(63)   Geib E, Baldeweg F, Doerfer M, Nett M, Brock M. Cross-Chemistry Leads to Product Diversity from Atromentin Synthetases in Aspergilli from Section Nigri. Cell Chem Biol. 2019 Feb 21;26(2):223-234.e6. doi: 10.1016/j.chembiol.2018.10.021. Epub 2018 Dec 6. PMID: 30527997.

(62)   Kurth C, Wasmuth I, Wichard T, Pohnert G, Nett M. Algae induce siderophore biosynthesis in the freshwater bacterium Cupriavidus necator H16. Biometals. 2019 Feb;32(1):77-88. doi: 10.1007/s10534-018-0159-6. Epub 2018 Nov 24. PMID: 30474772.

(61)   Baldeweg F, Hoffmeister D, Nett M. Correction: A genomics perspective on natural product biosynthesis in plant pathogenic bacteria. Nat Prod Rep. 2020 Mar 25;37(3):464. doi: 10.1039/d0np90009e. Erratum for: Nat Prod Rep. 2019 Feb 20;36(2):307-325. PMID: 32104837.

(61)   Baldeweg F, Hoffmeister D, Nett M. A genomics perspective on natural product biosynthesis in plant pathogenic bacteria. Nat Prod Rep. 2019 Feb 20;36(2):307-325. doi: 10.1039/c8np00025e. Erratum in: Nat Prod Rep. 2020 Mar 25;37(3):464. PMID: 30063232.

2018

(60)   Korp J, Winand L, Sester A, Nett M. Engineering Pseudochelin Production in Myxococcus xanthus. Appl Environ Microbiol. 2018 Oct 30;84(22):e01789-18. doi: 10.1128/AEM.01789-18. PMID: 30217842; PMCID: PMC6210110.

2017

(59)   Baldeweg F, Kage H, Schieferdecker S, Allen C, Hoffmeister D, Nett M. Structure of Ralsolamycin, the Interkingdom Morphogen from the Crop Plant Pathogen Ralstonia solanacearum. Org Lett. 2017 Sep 15;19(18):4868-4871. doi: 10.1021/acs.orglett.7b02329. Epub 2017 Aug 28. PMID: 28846435.

(58)   Pan X, Domin N, Schieferdecker S, Kage H, Roth M, Nett M. Herpetopanone, a diterpene from Herpetosiphon aurantiacus discovered by isotope labeling. Beilstein J Org Chem. 2017 Nov 17;13:2458-2465. doi: 10.3762/bjoc.13.242. PMID: 29234472; PMCID: PMC5704754.

(57)   Pan X, Kage H, Martin K, Nett M. Herpetosiphon gulosus sp. nov., a filamentous predatory bacterium isolated from sandy soil and Herpetosiphon giganteus sp. nov., nom. rev. Int J Syst Evol Microbiol. 2017 Jul;67(7):2476-2481. doi: 10.1099/ijsem.0.002141. Epub 2017 Jul 26. PMID: 28741992.

(56)   Brandt P, García-Altares M, Nett M, Hertweck C, Hoffmeister D. Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase. Angew Chem Int Ed Engl. 2017 May 15;56(21):5937-5941. doi: 10.1002/anie.201700767. Epub 2017 Apr 25. PMID: 28440038.

(55)   Valiante V, Mattern DJ, Schüffler A, Horn F, Walther G, Scherlach K, Petzke L, Dickhaut J, Guthke R, Hertweck C, Nett M, Thines E, Brakhage AA. Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus. ACS Chem Biol. 2017 May 19;12(5):1227-1234. doi: 10.1021/acschembio.7b00003. Epub 2017 Mar 15. PMID: 28233494.

(54)   Schieferdecker S, König S, Pace S, Werz O, Nett M. Myxochelin-Inspired 5-Lipoxygenase Inhibitors: Synthesis and Biological Evaluation. ChemMedChem. 2017 Jan 5;12(1):23-27. doi: 10.1002/cmdc.201600536. Epub 2016 Nov 29. PMID: 27875023.

2016

(53)   Braga D, Hoffmeister D, Nett M. A non-canonical peptide synthetase adenylates 3-methyl-2-oxovaleric acid for auriculamide biosynthesis. Beilstein J Org Chem. 2016 Dec 16;12:2766-2770. doi: 10.3762/bjoc.12.274. PMID: 28144348; PMCID: PMC5238615.

(52)   Walther E, Boldt S, Kage H, Lauterbach T, Martin K, Roth M, Hertweck C, Sauerbrei A, Schmidtke M, Nett M. Zincophorin - biosynthesis in Streptomyces griseus and antibiotic properties. GMS Infect Dis. 2016 Nov 28;4:Doc08. doi: 10.3205/id000026. PMID: 30671322; PMCID: PMC6301713.

(51)   Kurth C, Kage H, Nett M. Siderophores as molecular tools in medical and environmental applications. Org Biomol Chem. 2016 Sep 21;14(35):8212-27. doi: 10.1039/c6ob01400c. Epub 2016 Aug 5. PMID: 27492756.

(50)   Seccareccia I, Kovács ÁT, Gallegos-Monterrosa R, Nett M. Unraveling the predator-prey relationship of Cupriavidus necator and Bacillus subtilis. Microbiol Res. 2016 Nov;192:231-238. doi: 10.1016/j.micres.2016.07.007. Epub 2016 Aug 3. PMID: 27664741.

(49)   Kalb D, Heinekamp T, Schieferdecker S, Nett M, Brakhage AA, Hoffmeister D. An Iterative O-Methyltransferase Catalyzes 1,11-Dimethylation of Aspergillus fumigatus Fumaric Acid Amides. Chembiochem. 2016 Oct 4;17(19):1813-1817. doi: 10.1002/cbic.201600293. Epub 2016 Aug 18. PMID: 27442960.

(48)   Schaible AM, Filosa R, Krauth V, Temml V, Pace S, Garscha U, Liening S, Weinigel C, Rummler S, Schieferdecker S, Nett M, Peduto A, Collarile S, Scuotto M, Roviezzo F, Spaziano G, de Rosa M, Stuppner H, Schuster D, D'Agostino B, Werz O. The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo. Biochem Pharmacol. 2016 Jul 15;112:60-71. doi: 10.1016/j.bcp.2016.04.019. Epub 2016 May 5. PMID: 27157409.

(47)   Schwenk D, Brandt P, Blanchette RA, Nett M, Hoffmeister D. Unexpected Metabolic Versatility in a Combined Fungal Fomannoxin/Vibralactone Biosynthesis. J Nat Prod. 2016 May 27;79(5):1407-14. doi: 10.1021/acs.jnatprod.6b00147. Epub 2016 Apr 22. PMID: 27104866.

(46)   Kurth C, Schieferdecker S, Athanasopoulou K, Seccareccia I, Nett M. Variochelins, Lipopeptide Siderophores from Variovorax boronicumulans Discovered by Genome Mining. J Nat Prod. 2016 Apr 22;79(4):865-72. doi: 10.1021/acs.jnatprod.5b00932. Epub 2016 Mar 29. PMID: 27023373.

(45)   Korp J, Vela Gurovic MS, Nett M. Antibiotics from predatory bacteria. Beilstein J Org Chem. 2016 Mar 30;12:594-607. doi: 10.3762/bjoc.12.58. PMID: 27340451; PMCID: PMC4902038.

(44)   Schieferdecker S, Nett M (2016) A fast and efficient method for the preparation of the 5-lipoxygenase inhibitor myxochelin A. Tetrahedron Lett. 57, 1359-1360. doi: 10.1016/j.tetlet.2016.02.047

2015

(43)   Kage H, Riva E, Parascandolo JS, Kreutzer MF, Tosin M, Nett M. Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase. Org Biomol Chem. 2015 Dec 21;13(47):11414-7. doi: 10.1039/c5ob02009c. Epub 2015 Oct 28. PMID: 26507693.

(42)   Korp J, König S, Schieferdecker S, Dahse HM, König GM, Werz O, Nett M. Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5-Lipoxygenase Inhibitors. Chembiochem. 2015 Nov;16(17):2445-50. doi: 10.1002/cbic.201500446. Epub 2015 Oct 13. PMID: 26416255.

(41)   Bauer JS, Ghequire MG, Nett M, Josten M, Sahl HG, De Mot R, Gross H. Biosynthetic Origin of the Antibiotic Pseudopyronines A and B in Pseudomonas putida BW11M1. Chembiochem. 2015 Nov;16(17):2491-7. doi: 10.1002/cbic.201500413. Epub 2015 Oct 28. PMID: 26507104.

(40)   Seccareccia I, Kost C, Nett M. Quantitative Analysis of Lysobacter Predation. Appl Environ Microbiol. 2015 Oct;81(20):7098-105. doi: 10.1128/AEM.01781-15. Epub 2015 Jul 31. PMID: 26231654; PMCID: PMC4579460.

(39)   Medema MH, Kottmann R, Yilmaz P,  ..., Nett M, ..., Breitling R, Takano E, Glöckner FO. Minimum Information about a Biosynthetic Gene cluster. Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. PMID: 26284661; PMCID: PMC5714517.

(38)   Schieferdecker S, Domin N, Hoffmeier C, Bryant DA, Roth M, Nett M (2015) Structure and absolute configuration of auriculamide, a natural product from the predatory bacterium Herpetosiphon aurantiacus. Eur. J. Org. Chem. 2015, 3057-3062. doi: 10.1002/ejoc.201500181

(37)   Schieferdecker S, König S, Koeberle A, Dahse HM, Werz O, Nett M. Myxochelins target human 5-lipoxygenase. J Nat Prod. 2015 Feb 27;78(2):335-8. doi: 10.1021/np500909b. Epub 2015 Feb 16. PMID: 25686392.

(36)   Barnes EC, Bezerra-Gomes P, Nett M, Hertweck C. Dandamycin and chandrananimycin E, benzoxazines from Streptomyces griseus. J Antibiot (Tokyo). 2015 Jul;68(7):463-8. doi: 10.1038/ja.2015.10. Epub 2015 Feb 18. PMID: 25690358.

2014

(35)   Nett M. Genome mining: concept and strategies for natural product discovery. Prog Chem Org Nat Prod. 2014;99:199-245. doi: 10.1007/978-3-319-04900-7_4. PMID: 25296440.

(34)   Schwenk D, Nett M, Dahse HM, Horn U, Blanchette RA, Hoffmeister D. Injury- induced biosynthesis of methyl-branched polyene pigments in a white-rotting basidiomycete. J Nat Prod. 2014 Dec 26;77(12):2658-63. doi: 10.1021/np500552a. Epub 2014 Nov 24. PMID: 25420175.

(33)   Schieferdecker S, König S, Weigel C, Dahse HM, Werz O, Nett M. Structure and biosynthetic assembly of gulmirecins, macrolide antibiotics from the predatory bacterium Pyxidicoccus fallax. Chemistry. 2014 Nov 24;20(48):15933-40. doi: 10.1002/chem.201404291. Epub 2014 Oct 6. PMID: 25287056.

(32)   Pauly J, Nett M, Hoffmeister D. Ralfuranone Is Produced by an Alternative Aryl-Substituted γ-Lactone Biosynthetic Route in Ralstonia solanacearum. J Nat Prod. 2014 Aug 22;77(8):1967-71. doi: 10.1021/np500263r. PMID: 25033087.

(31)   Schieferdecker S, Exner TE, Gross H, Roth M, Nett M. New myxothiazols from the predatory bacterium Myxococcus fulvus. J Antibiot (Tokyo). 2014 Jul;67(7):519-25. doi: 10.1038/ja.2014.31. Epub 2014 Apr 2. PMID: 24690915.

(30)   Otzen C, Bardl B, Jacobsen ID, Nett M, Brock M. Candida albicans utilizes a modified β-oxidation pathway for the degradation of toxic propionyl-CoA. J Biol Chem. 2014 Mar 21;289(12):8151-69. doi: 10.1074/jbc.M113.517672. Epub 2014 Feb 4. PMID: 24497638; PMCID: PMC3961645.

(29)   Kreutzer MF, Kage H, Herrmann J, Pauly J, Hermenau R, Müller R, Hoffmeister D, Nett M. Precursor-directed biosynthesis of micacocidin derivatives with activity against Mycoplasma pneumoniae. Org Biomol Chem. 2014 Jan 7;12(1):113-8. doi: 10.1039/c3ob41839a. Epub 2013 Nov 8. PMID: 24202877.

2013

(28)   Pauly J, Spiteller D, Linz J, Jacobs J, Allen C, Nett M, Hoffmeister D. Ralfuranone thioether production by the plant pathogen Ralstonia solanacearum. Chembiochem. 2013 Nov 4;14(16):2169-78. doi: 10.1002/cbic.201300364. Epub 2013 Sep 17. PMID: 24106142.

(27)   Kage H, Kreutzer MF, Wackler B, Hoffmeister D, Nett M. An iterative type I polyketide synthase initiates the biosynthesis of the antimycoplasma agent micacocidin. Chem Biol. 2013 Jun 20;20(6):764-71. doi: 10.1016/j.chembiol.2013.04.010. PMID: 23790487.

(26)   Gurovic MSV, Müller S, Domin N, Seccareccia I, Nietzsche S, Martin K, Nett M. Micromonospora schwarzwaldensis sp. nov., a producer of telomycin, isolated from soil. Int J Syst Evol Microbiol. 2013 Oct;63(Pt 10):3812-3817. doi: 10.1099/ijs.0.051623-0. Epub 2013 May 10. PMID: 23667141.

(25)   Kersten RD, Lane AL, Nett M, Richter TK, Duggan BM, Dorrestein PC, Moore BS. Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica. Chembiochem. 2013 May 27;14(8):955-62. doi: 10.1002/cbic.201300147. Epub 2013 May 3. PMID: 23649992; PMCID: PMC3755882.

(24)   Elliott CE, Callahan DL, Schwenk D, Nett M, Hoffmeister D, Howlett BJ. A gene cluster responsible for biosynthesis of phomenoic acid in the plant pathogenic fungus, Leptosphaeria maculans. Fungal Genet Biol. 2013 Apr;53:50-8. doi: 10.1016/j.fgb.2013.01.008. Epub 2013 Feb 7. PMID: 23396262.

2012

(23)   Kreutzer MF, Nett M. Genomics-driven discovery of taiwachelin, a lipopeptide siderophore from Cupriavidus taiwanensis. Org Biomol Chem. 2012 Dec 21;10(47):9338-43. doi: 10.1039/c2ob26296g. Epub 2012 Sep 12. PMID: 22972004.

(22)   Kreutzer MF, Kage H, Nett M. Structure and biosynthetic assembly of cupriachelin, a photoreactive siderophore from the bioplastic producer Cupriavidus necator H16. J Am Chem Soc. 2012 Mar 21;134(11):5415-22. doi: 10.1021/ja300620z. Epub 2012 Mar 13. PMID: 22381697.

(21)   Kastner S, Müller S, Natesan L, König GM, Guthke R, Nett M. 4-Hydroxyphenylglycine biosynthesis in Herpetosiphon aurantiacus: a case of gene duplication and catalytic divergence. Arch Microbiol. 2012 Jun;194(6):557-66. doi: 10.1007/s00203-012-0789-y. Epub 2012 Feb 4. PMID: 22307823.

2011

(20)   Kiss H, Nett M, Domin N, Martin K, Maresca JA, Copeland A, Lapidus A, Lucas S, Berry KW, Glavina Del Rio T, Dalin E, Tice H, Pitluck S, Richardson P, Bruce D, Goodwin L, Han C, Detter JC, Schmutz J, Brettin T, Land M, Hauser L, Kyrpides NC, Ivanova N, Göker M, Woyke T, Klenk HP, Bryant DA. Complete genome sequence of the filamentous gliding predatory bacterium Herpetosiphon aurantiacus type strain (114-95(T)). Stand Genomic Sci. 2011 Dec 31;5(3):356-70. doi: 10.4056/sigs.2194987. Epub 2011 Dec 23. PMID: 22675585; PMCID: PMC3368417.

(19)   Nett M, Hertweck C. Farinamycin, a quinazoline from Streptomyces griseus. J Nat Prod. 2011 Oct 28;74(10):2265-8. doi: 10.1021/np2002513. Epub 2011 Sep 22. PMID: 21939253.

(18)   Kreutzer MF, Kage H, Gebhardt P, Wackler B, Saluz HP, Hoffmeister D, Nett M. Biosynthesis of a complex yersiniabactin-like natural product via the mic locus in phytopathogen Ralstonia solanacearum. Appl Environ Microbiol. 2011 Sep;77(17):6117-24. doi: 10.1128/AEM.05198-11. Epub 2011 Jul 1. PMID: 21724891; PMCID: PMC3165373.

(17)   Udwary DW, Gontang EA, Jones AC, Jones CS, Schultz AW, Winter JM, Yang JY, Beauchemin N, Capson TL, Clark BR, Esquenazi E, Eustáquio AS, Freel K, Gerwick L, Gerwick WH, Gonzalez D, Liu WT, Malloy KL, Maloney KN, Nett M, Nunnery JK, Penn K, Prieto-Davo A, Simmons TL, Weitz S, Wilson MC, Tisa LS, Dorrestein PC, Moore BS. Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses. Appl Environ Microbiol. 2011 Jun;77(11):3617-25. doi: 10.1128/AEM.00038-11. Epub 2011 Apr 15. PMID: 21498757; PMCID: PMC3127629.

(16)   Wackler B, Schneider P, Jacobs JM, Pauly J, Allen C, Nett M, Hoffmeister D. Ralfuranone biosynthesis in Ralstonia solanacearum suggests functional divergence in the quinone synthetase family of enzymes. Chem Biol. 2011 Mar 25;18(3):354-60. doi: 10.1016/j.chembiol.2011.01.010. PMID: 21439480.

(15)   Bohnert M, Miethbauer S, Dahse HM, Ziemen J, Nett M, Hoffmeister D. In vitro cytotoxicity of melleolide antibiotics: structural and mechanistic aspects. Bioorg Med Chem Lett. 2011 Apr 1;21(7):2003-6. doi: 10.1016/j.bmcl.2011.02.026. Epub 2011 Feb 12. PMID: 21376582.

(14)   Nett M, Roth M, Henkel T (2011) Genomics meets microfluidics. GENOMXPRESS 2.11, 8-9

2010

(13)   Gomes PB, Nett M, Dahse HM, Hertweck C. Pitucamycin: structural merger of a phenoxazinone with an epoxyquinone antibiotic. J Nat Prod. 2010 Sep 24;73(9):1461-4. doi: 10.1021/np100344u. PMID: 20715808.

(12)   Gomes PB, Nett M, Dahse H-M, Sattler I, Martin K, Hertweck C (2010) Bezerramycins A-C, antiproliferative phenoxazinones from Streptomyces griseus featuring carboxy, carboxamide or nitrile substituents. Eur. J. Org. Chem. 2010, 231-235. doi: 10.1002/ejoc.200901206

2009

(11)   Nett M, Ikeda H, Moore BS. Genomic basis for natural product biosynthetic diversity in the actinomycetes. Nat Prod Rep. 2009 Nov;26(11):1362-84. doi: 10.1039/b817069j. Epub 2009 Sep 1. PMID: 19844637; PMCID: PMC3063060.

(10)   Schneider P, Jacobs JM, Neres J, Aldrich CC, Allen C, Nett M, Hoffmeister D. The global virulence regulators VsrAD and PhcA control secondary metabolism in the plant pathogen Ralstonia solanacearum. Chembiochem. 2009 Nov 23;10(17):2730-2. doi: 10.1002/cbic.200900510. PMID: 19830761.

(9)   Nett M, Gulder TA, Kale AJ, Hughes CC, Moore BS. Function-oriented biosynthesis of beta-lactone proteasome inhibitors in Salinispora tropica. J Med Chem. 2009 Oct 8;52(19):6163-7. doi: 10.1021/jm901098m. PMID: 19746976; PMCID: PMC2771571.

(8)   Penn K, Jenkins C, Nett M, Udwary DW, Gontang EA, McGlinchey RP, Foster B, Lapidus A, Podell S, Allen EE, Moore BS, Jensen PR. Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria. ISME J. 2009 Oct;3(10):1193-203. doi: 10.1038/ismej.2009.58. Epub 2009 May 28. PMID: 19474814; PMCID: PMC2749086.

(7)   Nett M, Moore BS (2009) Exploration and engineering of biosynthetic pathways in the marine actinomycete Salinispora tropica. Pure Appl. Chem. 81, 1075-1084. doi: 10.1351/PAC-CON-08-08-08

2008

(6)   McGlinchey RP, Nett M, Eustáquio AS, Asolkar RN, Fenical W, Moore BS. Engineered biosynthesis of antiprotealide and other unnatural salinosporamide proteasome inhibitors. J Am Chem Soc. 2008 Jun 25;130(25):7822-3. doi: 10.1021/ja8029398. Epub 2008 May 31. PMID: 18512922; PMCID: PMC2814216.

(5)   McGlinchey RP, Nett M, Moore BS. Unraveling the biosynthesis of the sporolide cyclohexenone building block. J Am Chem Soc. 2008 Feb 27;130(8):2406-7. doi: 10.1021/ja710488m. Epub 2008 Jan 31. PMID: 18232689.

2007

(4)   Nett M, König GM. The chemistry of gliding bacteria. Nat Prod Rep. 2007 Dec;24(6):1245-61. doi: 10.1039/b612668p. Epub 2007 May 25. PMID: 18033578.

2006

(3)   Nett M, Erol O, Kehraus S, Köck M, Krick A, Eguereva E, Neu E, König GM. Siphonazole, an unusual metabolite from Herpetosiphon sp. Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3863-7. doi: 10.1002/anie.200504525. PMID: 16671154.

2003

(2)   Gross H, Kehraus S, Nett M, König GM, Beil W, Wright AD. New cytotoxic cembrane based diterpenes from the soft corals Sarcophyton cherbonnieri and Nephthea sp. Org Biomol Chem. 2003 Mar 21;1(6):944-9. doi: 10.1039/b210039h. PMID: 12929632.

2002

(1)   Nett M, Fenske D (2002) Substitution von Betablockern. Krankenhauspharmazie 23, 509-513

Patente

2016

(1)   Surup F, Steinmetz H, Mohr K, Viehrig K, Müller R, Nett M, Schieferdecker S, Dahse H-M, Wolling M, Kirschning A (2016) Novel macrolide antibiotics. WO/2016/005049