Enzymatic biotransformations and enzyme reactors (Winand)
Enzymes that are isolated from microorganisms are also used in many different industrial applications, e.g, as additives in laundry detergents or in the baking industry. Enzymes are also becoming increasingly important in the production of pharmaceuticals, especially when classical methods of chemical synthesis fail. In our research, we produce and study enzymes that catalyze the synthesis of bioactive natural products. In addition, we are working on technical applications for enzymes, for example by designing enzyme reactors.
Publications
[1] L. Winand, D. J. Vollmann, J. Hentschel, M. Nett
Characterization of a Solvent-Tolerant Amidohydrolase Involved in Natural Product Heterocycle Formation
Catalysts. 2021, 11(8), 892. doi:10.3390/catal11080892
[2] L. Winand, S. Theisen, S. Lütz, K. Rosenthal, M. Nett
Immobilization of the Amidohydrolase MxcM and Its Application for Biocatalytic Flow Synthesis of Pseudochelin A
Catalysts. 2023, 13(2), 229. doi:10.3390/catal13020229