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Fakultät BCI

Engineering of Molecular Assembly Lines

The knowledge how natural products are assembled provides a vast number of opportunities to manipulate their biosynthesis in a rational way in order to expand the naturally occurring structural diversity. Our main efforts are directed towards unraveling the programming and plasticity of biosynthetic enzymes, especially polyketide synthases and nonribosomal peptide synthetases. The objective is to utilize these biocatalysts in a combinatorial fashion for the production of custom molecules. 

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